| DSM-5 will not include caffeine use disorder, although research shows that as little as two to three cups of coffee can trigger a withdrawal effect marked by tiredness or sleepiness | There is sufficient evidence to support this as a condition, however it is not yet clear to what extent it is a clinically significant disorder |
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| Additionally, the diagnosis of dependence caused much confusion | A withdrawal syndrome characterized by drowsiness, irritability, and headache typically lasts no longer than a day |
Substance use disorder in DSM-5 combines the DSM-IV categories of substance abuse and substance dependence into a single disorder measured on a continuum from mild to severe.
7| "Chapter 15: Reinforcement and Addictive Disorders" | Long-term caffeine use can lead to mild physical dependence |
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